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It is mainly stored in skeletal muscle, but is also found in plasma (although in much lower concentrations)

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Mitochondrial dysfunction is recognized as one of the primary hallmarks of biological aging, and MOTS-c directly addresses this mechanism

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Biological age and telomere lengths were measured at baseline, 9 months, and 16 months using TruAge

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The low adverse effects observed in patients treated with pegylated arginase I suggest pegylated arginase I may be a good candidate as an arginine depletor for cancer treatment

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