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Oncol 33, 992999 (2015)

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M.MirhosseiniY.KhaksariM.et al (2021)

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As members of the dioxygenase family, they are cytosine demethylases in DNA, RNA, and histones, such as the ten-eleven translocation enzyme (TET) dioxygenase family, DNA and RNA demethylases of the AlkB homolog (ALKBH) family and Jumonji C domain-containing histone demethylases (JHDMs) ( 2+ state in the catalytic cycle of TET, thus increasing the oxidation rate of 5mC up to 8-fold in a dose- and time-dependent manner (Yin et al., 2013