These alterations include biochemical defects, such as impaired control of glutamate metabolism (the major neurotransmitter) [304], as well as the loss of synaptic activity and dendrites [305], apoptosis of neurons primarily in the ganglion cell and inner nuclear layers [306,307], and the activation of microglial cells that may protect the inner retina from injury and contribute to the inflammatory response [308]
JanuchowskiRWojtowiczKSterzy?skaKSosi?skaPAndrzejewskaMZawieruchaPet al
This is notable in the light of the observation from cohort studies that the association of serum UA with PD is also stronger in males 12
Always follow your own institutions handling protocols for research compounds.
Veyrat-Durebex C, Reynier P, Procaccio V, Hergesheimer R, Corcia P, andres CR, et al