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[61,] [62 ]These results were criticized on a number of grounds, including the noticeable difference between the vitamin C and placebo, lack of intravenous administration, and termination of treatment with tumor progression

Interestingly, when compared to the GN-treated group, the carrier NPs-CS and -spanlastics did not significantly modify renal parameters, indicating that they did not worsen damage processes or impair baseline renal function