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For example, in mouse embryonic stem cells, excess 2-OG maintains pluripotency dependent on the 2-OG/succinate ratio by increasing TET and KDM activity 45

Always measure the calculated volume precisely to achieve your intended concentration

Instead of stopping, pulling out, and starting over properly, I told myself it would be fine and pushed the plunger anyway

This systems-level modulation is both an opportunity (for comprehensive disease modification) and a challenge (for precision and predictability)

In P13 and P15, who had evidence of collagen flowers on skin biopsy, DNA analysis of COL5A1 and COL5A2 was performed, which did not show abnormalities