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100,125,126 The preferred sulphur-accepting substrate is still a matter of debate, but glutathione appears to be the most effective and plausible in physiological conditions

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NAC, in particular, has been shown to increase glutathione levels in the liver and other tissues (1)

H3K27me3 and H3K4me3 can co-occupy the same promoters and such bivalent chromatin structure is thought to allow fast activation of gene expression (Bernstein et al., 2006