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The activation of PKC results in phosphorylation of downstream kinases leading to activation of the MAPK signaling pathway

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A multimodal intervention study combining omega-3 supplementation (~2 grams per day) with moderate exercise in patients with malignant lung and pancreatic cancers resulted in an average weight gain of 4.5% and an improvement in muscle mass after 6 weeks, compared with continued weight loss in the control group (77)

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