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Due to their discontinuous distribution in tumors, which enhances the enhanced permeability and retention (EPR) effect, nanoparticles traverse cancerous cells more efficiently than surrounding normal tissue, exhibiting greater permeability

J., Vaida, F., Hu, K., Dube, M., Henry, B., Chow, F., Heaton, R

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Furthermore, when using cholesterol hydroperoxide (ChOOH, a specific GPX4 substrate) as a stressor, compound 102 could activate GPX4 in intact cells and protect them from ChOOH toxic effects ( Supplementary Figure S12B )

The most accurate answer is: they can support a weight-loss plan, but theyre not proven as a stand-alone weight-loss treatment