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Individualized protocols based on personal response optimize the balance between effectiveness and tolerability

[iv] Challenges Associated With FIH Trials Since these studies represent the first administration of an investigational drug in humans, they are associated with inherent challenges, especially safety

Kim S-J, Winter K, Nian C, et al

BPC-157 is not FDA approved for general medical use, so patients should avoid self-sourcing or guessing their own protocol

Growth/differentiation factor-15 (GDF-15) Another potential therapeutic pathway for obesity pharmacotherapies is through the stress-induced cytokine GDF-15, which is expressed in multiple cell types including cardiomyocytes, adipocytes and macrophages [98]