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This research demonstrated that MDD is characterized by nitrosative aberrations, which include elevated synthesis of iNOS and nitric oxide (NO), increased nitroso binding to proteins or hypernitrosylation, and autoimmune reactions to the newly generated nitroso-adducts [7]

Early failures underscored the complexity of ICH, whereas contemporary strategies emphasize antihypertensive therapy, neuroprotective and cytoprotective compounds, antioxidant and anti-inflammatory agents, ferroptosis inhibitors, multifunctional proteins such as HSA, and bioactive natural products

75 Most knowledge of metabolism comes from studying liver metabolism

Allergy 36, 115122

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