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Polarized macrophages were stimulated with 500 nM PMA at 37 C for 23 h and washed three times in RPMI 1640

We further determined that Norleual-AngIVs mechanism of action as a Met antagonist is by blocking HGF dimerization which, as indicated above, is a prerequisite to binding and activation of the Met receptor [82,83]

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Call 911 immediately if you have severe breathing difficulty, chest pain, or fainting, as these combinations can indicate life-threatening conditions like heart attack or blood clots

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