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It is different, however, in that it does not bind to IGFBPs
GHK-Cu suppresses inflammation through multiple signaling pathway interventions, reducing production of pro-inflammatory cytokines like TNF-alpha and IL-6 while decreasing inflammatory cell infiltration into tissues
When functionalized with fluoride ions (F - ), these systems exhibit synergistic antimicrobial-remineralizing dual functionality, presenting a promising strategy for secondary caries prevention and therapy (Qi et al., 2025)