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Cigarette smoke-activated macrophages released IL-1, tumor necrosis factor-alpha (TNF), and chemokine (C-X-C motif) ligand (CXCL), which additionally attracted monocytes, neutrophils, and lymphocytes from the bloodstream into the lungs (Figure 2)
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In addition to a patient history and physical examination, the cause of coughing up blood is diagnosed with tests such as: Chest X-ray Chest computerized tomography (CT) scan Blood tests Complete blood count (CBC) Blood chemistry Arterial blood gas Urinalysis Coagulation studies such as prothrombin time (PT) or partial thromboplastin time (PTT) Bronchoscopy Lung biopsy Lung scan Pulmonary arteriography Sputum culture and smear Pulse oximetry What Is the Treatment for Coughing Up Blood