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Early Signs and Symptoms of Vitamin B12 Deficiency: Fatigue, weakness, and lack of energy: These symptoms may be brought on by inadequate vitamin B12, which lowers the synthesis of red blood cells

Do not double up on doses to make up for a missed one, as this could increase the risk of potential side effects

Olasupo Odunsi, MD, Medical Director Reviewed July 5, 2026 If you're constantly tired and your metabolism feels stuck, low B12 could be part of the problem