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Reproductive aging in C57BL/6J mice: plasma progesterone, viable embryos and resorption frequency throughout pregnancy

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12 Half-Life, Duration of Action, and Dosing Drugs that have a short half-life stay in the body for a shorter period and so have a shorter duration of action

doi: 10.1172/JCI116442 196 OhgamiNNagaiRMiyazakiAIkemotoMAraiHHoriuchiSet al

If a nootropic asks you to cycle, or occasionally take a few days off from taking it, its likely that it contains ingredients that could build up in your system or that you could more easily develop a tolerance to over time