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The treatment of PEH is challenging: On the one hand, watchful waiting carries the risk of developing acute life-threatening complications requiring an emergency operation

Can also be used twice daily if necessary

Rotation of injection sites prevents localized tissue irritation and ensures consistent absorption

While a causal relationship has not been established, patients with depression or other psychiatric conditions should be monitored for changes in mood or behavior, particularly during the initial weeks of treatment or following dose adjustments

doi: 10.5005/jp-journals-10018-1159, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 79.Honda Y, Kessoku T, Sumida Y, Kobayashi T, Kato T, Ogawa Y, et al