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1.1 Glutathione peroxidase Glutathione peroxidase (GPx) an mammalian enzyme, contains selenocysteine residue in its active site, For the last four decades, an extensive research has been carried out on the mammalian antioxidant enzymes GPx [34]

doi: 10.1038/s41467-021-26437-y 31 ThanNGHahnSRossiSWSzekeres-BarthoJ

Nat Rev Mol Cell Biol (2016) 17:61125

By simultaneously targeting upstream stressors (ROS and AGEs) instead of solely inhibiting tyrosinase activity, DEC addresses the key drivers of hyperpigmentation with a favorable safety profile

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