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doi:10.1016/j.pharmthera.2021.107916

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This time is determined solely by the drug's elimination half-life (t 1/2 ) and is independent of the size of the dose or the frequency of the dosing interval

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Chemical hydrolysis Chemical hydrolysis breaks down proteins using acids like hydrochloric acid (Ashaolu, 2020) or bases such as calcium, sodium, or potassium hydroxide (lvarezVias et al., 2020)