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The mechanisms controlling their transcription, post-transcriptional mRNA fate and post-translational modifications remain largely uncharacterized

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The non-24-hour sleep-wake rhythm disorder is most commonly seen in blindness, since the light-dark cycle is the most powerful cue for synchronizing the hypothalamic pacemaker to the 24-hour day (103)

Its compact tripeptide structure ensures rapid diffusion into fibroblast, keratinocyte, and endothelial models, while its copper chelate enables robust activation of lysyl oxidase and superoxide dismutase