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Skin lacking firmness and elasticity

If you pick up a vial weeks later and cannot remember how much water you added, you have no way to calculate accurate doses

this model is static PES improves separation but remains a single perturbation snapshot MEA captures correlates of state transitions, not full continuous dynamics This paper shows local cortical dynamics only (not whole-brain physiology) so results are: developmental-stage dependent model-specific (2D organoid in vivo brain) perturbation-dependent Why fully dynamic modeling is nearly impossible

This results in the accumulation of damaged mitochondria, thereby establishing a vicious cycle in which mitochondrial damage leads to increased ROS, which in turn promotes ferroptosis

10.1016/j.envint.2019.104938 19 ChopraS.KumarD