The presence of multiple GSTs with overlapping functions and substrate specificities might preclude the observation of phenotypic alteration in knockout mutants (Sappl et al., We propose a model describing the diverse roles of plant GSTs in the interactions of plant hosts with pathogenic microbes considering four different plant-pathogen interaction types (Table 1): (1) symptomless resistance (including basal resistance to bacteria and symptomless R gene-mediated resistance to viruses), (2) HR-associated resistance, (3) limiting susceptibility to systemic spread of pathogens and plant cell/tissue death (during infections by hemibiotrophic/necrotrophic fungi, bacteria, and viruses), (4) promoting susceptibility to biotrophic fungi and viruses (maintaining reduced conditions in infected non-necrotic plant tissues)
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Glutathione, known for its detoxifying properties, plays a critical role in supporting the immune system, enhancing metabolic functions, and promoting overall health
Aids digestion and supports healthy gut flora
The potential role of their binding to the membrane will also be addressed
