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The absence of significant effects of caffeine administration on LV long-axis indices observed in this study confirms early reports that found no effects on standard indices of LV systolic and diastolic function [26], and strengthens this hypothesis by showing that functional changes after caffeine assumption cannot be detected even when sensitive indices of ventricular function are considered

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Nicotine does not cause cancer - unlike tobacco in normal cigarettes, which kills thousands of smokers every year

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