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Data Collection All patients had been sedated by continuous infusion of propofol and opioid, and were fully adapted to volume-controlled mode with a tidal volume (Vt) set at 7-9 ml/kg of ideal body weight, and a positive end-expiratory pressure (PEEP) of 5-15 cmH 2 O

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27 In general, patients with an irreversible cause should be treated indefinitely, whereas those with a reversible cause should be treated until the deficiency is corrected and symptoms resolve

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These findings have positioned 5-Amino-1MQ as a useful molecular tool for probing upstream metabolic regulation