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The translocation of these noxious metabolites into circulation can induce oxidative stress and systemic inflammation, subsequently aggravating renal inflammation and fibrosis

Citing these recent works will both address the reviewers concern about currency and strengthen the argument that GSH-responsive strategies are maturing toward precision, clinically relevant theranostics [20]

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sUA induces macrophage polarization toward the M2 type

Melatonin attenuates potato late blight by disrupting cell growth, stress tolerance, fungicide susceptibility and homeostasis of gene expression in Phytophthora infestans