In yeast, Ohsumis and Klionskys laboratories first identified that ATG32 acts as the mitophagy-specific receptor, which directly interacts with the selective autophagy adaptor ATG8 via an ATG8-interacting motif (AIM) and ATG11 to form the nascent autophagosome (Okamoto et al., 2009)
DEGs were identified using the DESeq2 R package, and results were visualized as a volcano plot using the ggplot2 R package ( Metabolic genes were defined based on a curated list 6,40
Iqbal J, Abbasi BA, Ahmad R, Batool R, Mahmood T, Ali B, et al
Nitric oxide synthases: Roles, tolls, and controls
Ebsworth has served as a Trustee of the Fund and the other trusts in the Fund Complex since January 1, 2015