Phase 2 only -- less safety data available
While we cannot disregard the possibility of some remaining effects of relaxation time differentials, we note that our results are metabolite-specific, while systematic between-group differences in relaxation times would likely impact all metabolite concentrations equally
Under normal physiological conditions, mitochondria exhibit a substantial negative charge, which causes the accumulation of TMRE within the mitochondrial matrix and produces intense orange-red fluorescence
The peptides don't interferethey're targeting different tissues through separate mechanisms
After assessment of the isolated bladder tissue, the levels of inflammatory proteins (TNF-, IL-6, glutathione peroxide, nitric oxide, etc.) were found to be lower in both mesna and extract-treated groups