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Several neurotrophic factors are also secreted by astrocytes, including brain-derived neurotrophic factor, glia-derived neurotrophic factor, nerve growth factor, basic fibroblast growth factor, VEGF, ciliary neurotrophic factor, and erythropoietin ( in vitro to stimulate the migration and proliferation of adult neural stem cells through the secretion of the neuroblast attracting chemokine stromal cell-derived factor-1 (211)