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[49] showed no change in oxidative stress as measured by F2-isoP levels in the group supplemented with a high dose of Se compared to the group with a standard dose of Se, which suggests using other oxidative damage markers along with F2-isoP may give a more complete picture of oxidative stress

This appears to be largely mediated through improvements in insulin sensitivity and weight loss, which reduce androgen excess and normalise hypothalamic-pituitary signalling

[49] These data show a correlation between zinc status and thyroid function, but they dont yet show a definitive improvement from zinc supplementation

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Hybridoma cells were subcloned five limiting dilution rounds to obtain the stable monoclonal cell clone MS4A 5E6 (rat IgG2c/)