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But, some patients might need more frequent doses

Arthritis Rheumatism 54 , 35333544 (2006)

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58.4% male, 38.0% aged 60 years, 81.9% upper limb spasticity only

After intravenous injection of autologous bone marrow-derived MSCs, we found the expression of IL-4, IL-10, and TGF-1 was increased by BM-MSCs through the inhibition of Th1 activity, thereby enhancing Treg function ( MCS can directly or indirectly regulates local matrix components through secreting vesicles or exosomes and promotes the repair of damaged joint tissues