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8 AquilanoK.VigilanzaP.FilomeniG.RotilioG.CirioloM

According to this hypothesis, 5OP would signal through pH modulation to activate PhoPQ, upregulating the mgtCBR operon, which would then regulate c-di-GMP, cellulose and cellular aggregation

The study protocol was in compliance with the Helsinki Declaration and was approved by the Regional Scientific Ethical Committees of Copenhagen in Denmark (Protocol nr.: 17003845