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For example, it may have been tested in an animal model, but not tested in a really rigorous double-blind clinical trial, which takes 10 to 15 years. She estimates that the entire process for bringing a drug from the lab to the market can cost about $2 billion

(3) Heme Oxygenase-1 (HO-1) Induction: CS upregulates HO-1, accelerating heme catabolism and subsequent iron release

Yakugaku Zasshi 128(9):13471353 Hu X, Tang R, Zhao C, Mu R, Wang Y, Cao Y, Zhang N, Fu Y (2021) The prevention effect of bacillus subtilis on escherichia coliinduced mastitis in mice by suppressing the NF-B and MAPK signaling pathways

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J Neurochem 92(4):798806 Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL (2015) Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain