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299 After using the mitophagy inducer urolithin A, increased mitophagy significantly down-regulated the mtDNA mediated cGAS-STING axis, thereby alleviating the inflammatory response caused by aging

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Higher doses dont have any clinical basis and may increase risk

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473,474 AMPK activate peroxisome proliferator-activated receptor coactivator-1 (PGC-1), the key factor in mitochondrial biogenesis, thus enhancing mitochondrial respiratory and metabolic functions