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Talal Khader is a board-certified physician specializing in family medicine

Furthermore, icariin extracted from Epimedium can also function as a GPER agonist by activating GPER and subsequently increasing the expression of sirtuin 1 (Sirt1), thereby reducing the translocation and release of high-mobility group box 1 (HMGB1) and inhibiting inflammation to improve endothelial function in type 1 diabetic rats [193]

In a randomized controlled trial, 11 obese participants received a dietary intervention that reduced their intake by 1,000 kcal, after 16 weeks their peripheral insulin sensitivity enhanced

In the central nervous system, oligodendrocytes (OLs) are a particularly specialized type of glial cell which provide fundamental support to neuronal activity by producing the myelin sheath (van Tilborg et al., 2016

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