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Where retatrutide likely falls Based on the pattern that greater weight loss correlates with greater hair shedding risk, and given that retatrutide produces the most aggressive weight loss of any medication in the class, the logical prediction is that retatrutide will show a hair loss incidence somewhere at or above tirzepatide levels (5% or higher) in large-scale clinical trials

Severe restriction worsens hair loss

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It's an ambiguity acknowledged by the review's authors, who state that more research is needed to clarify optimal amounts and to identify "sub-groups of individuals most likely to respond to particular nutrients or foods." Speaking with a doctor is your best first-line action to determine whether you could benefit from swapping dietary glutathione for a supplement, or vice versa

For example, a GLP- 1/oestradiol conjugate reduced feeding and body weight in several rodent models of the metabolic syndrome [139]