doi:10.1155/2015/648108 Pickart L, Vasquez-Soltero JM, Margolina A
One example in particular is if you are on TRT and use an Aromatase Inhibitor (AI) to keep your Estrogen levels in the sweet spot, having Berberine in your system may potentiate the effects of that AI (as the liver isn't breaking it down as efficiently as normal), which could potentially tank your Estrogen far below what it would normally be at on that same AI dosage without Berberine in your system
Composed of 23 amino acids in a D-amino acid configuration, this cell-penetrating peptide represents a novel therapeutic approach to addressing cellular senescence, a fundamental driver of aging and age-related diseases
If you have pernicious anemia, any kind of digestive condition, or you've had gastric surgery, your gut may not absorb B12 the way it should
Avoid freeze-thaw cycles, which can degrade peptide integrity