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Like other small peptides, glutathione is degraded by various peptidases including tripeptide aminopeptidases and -glutamyl transpeptidases 1,3

Other GPxs As studies of the functions of GPx5, GPx6 and GPx7 in the development of breast cancer are limited, it is difficult to determine their underlying mechanisms

Telomerase is a ribonucleoprotein enzyme responsible for maintaining telomere length at chromosome ends

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109 Therefore, BACH1 is possible to link ferroptosis with cancer EMT, and studying the function and regulation of BACH1 could enhance our understanding of the interaction between ferroptosis and EMT, providing guidance for developing new treatment strategies