Elevated cAMP activates protein kinase A (PKA), which then phosphorylates and activates hormone-sensitive lipase
While the overall number of therapeutics in use and in development looks encouraging at first glance particularly for PCOS with 45 marketed products and 88 candidates under investigation it is largely the result of a diversity of symptoms addressed individually with specific repurposed drugs and biologics, such as antibiotics to treat acne or fertility treatments
EMBO J 29:17921802 Rogov VV, Stolz A, Ravichandran AC et al (2017) Structural and functional analysis of the GABARAP interaction motif (GIM)
Yamane T, Murao S, Kozuka M, Shimizu M, Suzuki J, Kubo C, et al
Table Of Contents What Is Functional Medicine Testing