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Many EDS patients have shared that prolotherapy provided relief when nothing else did, for example, alleviating chronic neck pain from cervical instability or reducing the frequency of knee cap dislocations by tightening the surrounding ligaments

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92 Macrophages exposed to LEP upregulate M2 surface markers while producing M1 typical cytokines (TNF-, IL-6, IL-1), indicating that LEP regulates adipose tissue macrophage phenotype

High humidity can compromise vial integrity over time, potentially leading to contamination or degradation

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