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Claudins of intestine and nephrona correlation of molecular tight junction structure and barrier function

Sensation is assessed by asking patients to report when they perceive the first detectable sensation, the desire to defecate (or urgency), and maximal tolerable discomfort during rectal balloon distention, generally with a handheld syringe

74 However, because these results were never formally published in peer-reviewed journals, they have to be taken with caution