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Because FOXO4-DRIs mechanism depends on disrupting the FOXO4p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population leaving FOXO4-low non-senescent cells largely unaffected

Supplement Facts 120 Servings Serving Size: 1 capsule Serving Per Container: 60 * Percent Daily Values are based on a 2,000 calorie diet

Fratta Pasini et al., 2021), targeting Nrf2 is therefore essential for the treatment of diseases characterized by enhanced oxidative stress and inflammation, such as aging and COVID-19-induced pneumonia and ARDS (Lewis et al., 2010

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Office workers, athletes, tradespeople, musicians, and gamers all share vulnerability to these painful conditions