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Neurodegenerative diseases like Alzheimers, as too-high glutamate levels can affect brain function

After a one-hour incubation, the cells were washed three times with PBST and stained with DAPI

doi: 10.1056/NEJMOA1503734 266 OlsenSFsterdalMLSalvigJDMortensenLMRytterDSecherNJet al

Additionally, HDAC6 inhibitors activate redox-regulating proteins like peroxiredoxins (reduce ROS) and support the function of the autophagy and ubiquitin-proteasome system (UPS) (both are impaired in PD patients) 62