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The presence of a catechol group in the B-ring, due to its ability to donate hydrogen, increases the formation of a relatively stable flavonoid-derived radical, which is the most important determinant of reactive oxygen and nitrogen species (RONS) inhibition (188)

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The method of any one of embodiments 1-76, wherein the composition further comprises an excipient that decreases the release rate of the therapeutic agent

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As with any research compound, it is important to review available literature, understand study findings, and evaluate data carefully