They begin to suffer from anemia, nerve damage, and other problems
2015 Apr 30;9:2485-99
As interest in peptide science continues to expand, cagrilintide represents an important example of how advances in peptide engineering are enabling researchers to investigate increasingly sophisticated biological pathways
Results In both groups, mean serum vitamin B12 increased after 30 days of treatment and was maintained up to 90 days
For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation