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Thymosin beta-4 is the most abundant G-actin sequestering peptide in mammalian cells, maintaining the pool of unpolymerised actin monomers available for cytoskeletal dynamics, and was originally identified as a thymic hormone before its much broader roles in wound healing, angiogenesis, cell migration, anti-inflammatory biology, and tissue regeneration were characterised

doi: 10.1021/bi00018a020 Morris, MB, Ralston, GB, Biden, TJ, Browne, CL, King, GF and Iismaa, TP (1995)

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FUNDING This work was supported by the Russian Foundation for Basic Research (grant nos

Michael Howard, M.D