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In comparison between the matched groups, transgenders exhibited higher rates of smoking (aOR = 2.030), e-cigarette use (aOR = 3.651), binge drinking (aOR = 2.519), and alcohol consumption (aOR = 2.147)

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Uniquely, it had a time period at the end of the study where study medication was discontinued for 12 weeks, then reassessed to see if the treatment effects persisted