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When patients are prescribed isotretinoin, they must also register for the iPLEDGE program, in which all patients receive a monthly blood test and female patients of childbearing age receive a monthly pregnancy test, to monitor the effects of the drug on the body and prevent any serious birth defects

Dosage for Dogs: Administer 50 to 100 mg per kg of body weight, twice daily

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Kutzing and Firestein, 2007)

Bilosomes as Effective Delivery Systems to Improve the Gastrointestinal Stability and Bioavailability of Epigallocatechin Gallate (EGCG)