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145,146,147 DNA ligation The pathological DSBs are primarily repaired by the NHEJ, a process involves synapsis, end-processing and ligation

The pathogenesis of DN includes abnormal glucose metabolism, hyperperfusion and hyperfiltration of the kidney, oxidative stress, and inflammation

8,12 Death may occur as a consequence of complications associated with hepatic failure, including multiorgan system failure, cerebral edema, and sepsis

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Nutrients like biotin, vitamin C, glutathione, and collagen-boosting amino acids improve skin elasticity, hydrate from within, and strengthen hair and nails