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To smooth the RMSD data, a moving average was constructed for the 9 data sets (Supplementary Figures S5058)

*While bariatric surgery has very limited (if any) effect on lipedematous tissue directly, non-lipedema fat and obesity can be reduced

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This quality can be especially crucial for those with confirmed B12 deficiency or specific nerve pain conditions, where a quicker and more targeted approach can bring pain reduction benefits rapidly