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Nonetheless, it should be used within a certain timeframe as recommended by the pharmacy (often 28 days after first puncture, per general guidelines for multi-dose vials, unless otherwise specified)

Reduce if you are unable to maintain adequate hydration or nutrition at the current dose

Lim, L.S., Mitchell, P., Seddon, J.M., Holz, F.G., Wong, T.Y., Age-related macular degeneration