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Beyond its observed roles in vascular plants, -CC has been detected in cyanobacteria, microalgae, lichens, mosses, and fungi, suggesting that -carotene cleavage and its signaling derivatives arose early in evolution (Zuo, 2023)

p = 0.0002) significantly reduced acute exacerbation frequency

Lactobacilli and Bifidobacteriaceae have a significantly lower adjustment requirement of T4, indicating that the supplement of microbiota has increased levothyroxine availability and stabilizes thyroid function [140]

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T1D, on the other hand, in which the insulin-producing beta cells are destroyed, is potentially irreversible